TXA - Revision history

Treloars: /* Section 8 - MEDICATION GUIDELINES */

2025-07-28T16:33:45Z

Section 8 - MEDICATION GUIDELINES

← Older revision		Revision as of 16:33, 28 July 2025
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	'''CONTRAINDICATION'''		'''CONTRAINDICATION'''
	* Hypersensitivity to TXA		* Hypersensitivity to TXA
	* Should not be given more ~~then~~ 3 hours from when severe bleeding event started.		* Should not be given more than 3 hours from when severe bleeding event started.

	'''RELATIVE CONTRAINDICATIONS'''		'''RELATIVE CONTRAINDICATIONS'''

Treloars at 16:31, 28 July 2025

2025-07-28T16:31:59Z

← Older revision		Revision as of 16:31, 28 July 2025
Line 16:		Line 16:
	'''CONTRAINDICATION'''		'''CONTRAINDICATION'''
	* Hypersensitivity to TXA		* Hypersensitivity to TXA
			* Should not be given more then 3 hours from when severe bleeding event started.

	'''RELATIVE CONTRAINDICATIONS'''		'''RELATIVE CONTRAINDICATIONS'''

Treloars at 15:10, 8 February 2021

2021-02-08T15:10:31Z

← Older revision		Revision as of 15:10, 8 February 2021
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	* Safe in breastfeeding		* Safe in breastfeeding

	'''~~CONTRAINDICATIONS~~'''		'''CONTRAINDICATION'''
	* Hypersensitivity to TXA		* Hypersensitivity to TXA

	'''RELATIVE ~~CONTRAINDICATION~~'''		'''RELATIVE CONTRAINDICATIONS'''
	* Colorblindness		* Colorblindness
	* History of Seizures		* History of Seizures

Treloars at 15:10, 8 February 2021

2021-02-08T15:10:18Z

← Older revision		Revision as of 15:10, 8 February 2021
Line 16:		Line 16:
	'''CONTRAINDICATIONS'''		'''CONTRAINDICATIONS'''
	* Hypersensitivity to TXA		* Hypersensitivity to TXA

			'''RELATIVE CONTRAINDICATION'''
	* Colorblindness		* Colorblindness
	* History of Seizures		* History of Seizures

Treloars: /* Tranexamic Acid (TXA) */

2020-10-12T13:47:21Z

Tranexamic Acid (TXA)

← Older revision		Revision as of 13:47, 12 October 2020
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	* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.		* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.
	'''INDICATIONS'''		'''INDICATIONS'''
	* [[Hemorrhagic Shock\|Severe Hemorrhagic Shock]].		* [[Hemorrhagic Shock\|Severe Hemorrhagic Shock]] or imminent shock.
	*Strongly consider in non-traumatic bleeding (post-partum, gastrointestinal, postoperative, nasal)		*Strongly consider in non-traumatic major bleeding (post-partum, gastrointestinal, postoperative, nasal) with signs of shock or imminent shock.

	'''PREGNANCY CATEGORY'''		'''PREGNANCY CATEGORY'''

Treloars: Created page with "==Section 8 - MEDICATION GUIDELINES== ===ANTI-FIBRINOLYTICS=== ====Tranexamic Acid (TXA)==== '''DESCRIPTION''' * Inhibits both plasminogen activation and plasmin activity, t..."

2020-04-24T14:47:42Z

Created page with "==Section 8 - MEDICATION GUIDELINES== ===ANTI-FIBRINOLYTICS=== ====Tranexamic Acid (TXA)==== '''DESCRIPTION''' * Inhibits both plasminogen activation and plasmin activity, t..."

New page

==Section 8 - MEDICATION GUIDELINES==
===ANTI-FIBRINOLYTICS===

====Tranexamic Acid (TXA)====

'''DESCRIPTION'''
* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.
'''INDICATIONS'''
* [[Hemorrhagic Shock|Severe Hemorrhagic Shock]].
*Strongly consider in non-traumatic bleeding (post-partum, gastrointestinal, postoperative, nasal)

'''PREGNANCY CATEGORY'''
* B - Safe in Pregnancy
* Safe in breastfeeding

'''CONTRAINDICATIONS'''
* Hypersensitivity to TXA
* Colorblindness
* History of Seizures
* Ischemic event: Myocardial Infarction, stroke, pulmonary embolism (PE), deep venous thrombosis (DVT)
* Isolated head injury / subarachnoid hemorrhage

'''PRECAUTIONS'''
* Rapid injection can cause hypotension
'''DOSAGE'''
* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.
* 20mg/kg (1000mg maximum) TXA mixed in 100 ml of Normal Saline infused via IO or IV over 10 minutes.

[[Category:Medication Guidelines|TXA]]