Anti-Fibrinolytic - Revision history

Treloars at 19:21, 10 July 2019

2019-07-10T19:21:01Z

← Older revision		Revision as of 19:21, 10 July 2019
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	'''INDICATIONS'''		'''INDICATIONS'''
	* [[Hemorrhagic Shock\|Severe Hemorrhagic Shock]].		* [[Hemorrhagic Shock\|Severe Hemorrhagic Shock]].
			*Strongly consider in non-traumatic bleeding (post-partum, gastrointestinal, postoperative, nasal)

			'''PREGNANCY CATEGORY'''
			* B - Safe in Pregnancy
			* Safe in breastfeeding

	'''CONTRAINDICATIONS'''		'''CONTRAINDICATIONS'''
	* ~~Isolated head injury~~		* Hypersensitivity to TXA
	* ~~Known hypersensitivity~~		* Colorblindness
	* ~~Age less than 16 years old~~		* History of Seizures
	* ~~Known pregnancy~~		* Ischemic event: Myocardial Infarction, stroke, pulmonary embolism (PE), deep venous thrombosis (DVT)
			* Isolated head injury / subarachnoid hemorrhage

	'''PRECAUTIONS'''		'''PRECAUTIONS'''
	* Rapid injection can cause hypotension		* Rapid injection can cause hypotension
	'''DOSAGE'''		'''DOSAGE'''
	* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes. ~~Should be administered~~ via ~~a rate limiting device such as a Dial-A-Flo~~. ~~A Buretrol is not a rate limiting device.~~		* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.
			* 20mg/kg (1000mg maximum) TXA mixed in 100 ml of Normal Saline infused via IO or IV over 10 minutes.

	[[Category:Medication Guidelines\|0819]]		[[Category:Medication Guidelines\|0819]]

Treloars: /* Section 8 - MEDICATION GUIDELINES */

2018-10-30T15:55:25Z

Section 8 - MEDICATION GUIDELINES

← Older revision		Revision as of 15:55, 30 October 2018
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	* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.		* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.
	'''INDICATIONS'''		'''INDICATIONS'''
	* [[Shock\|Severe Hemorrhagic Shock]].		* [[Hemorrhagic Shock\|Severe Hemorrhagic Shock]].
	'''CONTRAINDICATIONS'''		'''CONTRAINDICATIONS'''
	* Isolated head injury		* Isolated head injury

Treloars at 20:43, 1 October 2018

2018-10-01T20:43:57Z

← Older revision		Revision as of 20:43, 1 October 2018
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	* Rapid injection can cause hypotension		* Rapid injection can cause hypotension
	'''DOSAGE'''		'''DOSAGE'''
	* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.		* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes. Should be administered via a rate limiting device such as a Dial-A-Flo. A Buretrol is not a rate limiting device.

	[[Category:Medication Guidelines\|0819]]		[[Category:Medication Guidelines\|0819]]

Treloars at 18:29, 7 September 2018

2018-09-07T18:29:59Z

← Older revision		Revision as of 18:29, 7 September 2018
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	* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.		* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.

	[[Category:Medication Guidelines\|~~0818~~]]		[[Category:Medication Guidelines\|0819]]

Treloars: Created page with "==Section 8 - MEDICATION GUIDELINES== ===8.19 ANTI-FIBRINOLYTICS=== ====Tranexamic Acid (TXA)==== '''DESCRIPTION''' * Inhibits both plasminogen activation and plasmin activi..."

2018-08-27T20:44:52Z

Created page with "==Section 8 - MEDICATION GUIDELINES== ===8.19 ANTI-FIBRINOLYTICS=== ====Tranexamic Acid (TXA)==== '''DESCRIPTION''' * Inhibits both plasminogen activation and plasmin activi..."

New page

==Section 8 - MEDICATION GUIDELINES==
===8.19 ANTI-FIBRINOLYTICS===

====Tranexamic Acid (TXA)====

'''DESCRIPTION'''
* Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.
'''INDICATIONS'''
* [[Shock|Severe Hemorrhagic Shock]].
'''CONTRAINDICATIONS'''
* Isolated head injury
* Known hypersensitivity
* Age less than 16 years old
* Known pregnancy
'''PRECAUTIONS'''
* Rapid injection can cause hypotension
'''DOSAGE'''
* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.

[[Category:Medication Guidelines|0818]]